Certification for IRB Professionals (CIP) Practice Exam

Who is typically excluded from IRB membership?

1. Individuals with no legal background

2. Individuals with conflicting interests in the research

3. Individuals who are research participants

4. Individuals with experience in human subject research

The correct answer is: Individuals with conflicting interests in the research

The correct answer highlights that individuals with conflicting interests in the research are typically excluded from IRB membership to maintain the integrity and objectivity of the review process. The primary role of an Institutional Review Board (IRB) is to safeguard the rights and welfare of human subjects involved in research. If a member has a conflicting interest, such as financial ties, personal relationships, or other connections to the research being reviewed, their participation could bias the review process or compromise ethical oversight. Excluding individuals with conflicting interests helps ensure that decisions made by the IRB are impartial and centered solely on the welfare of research participants. This practice aligns with ethical standards and regulatory requirements, which are aimed at minimizing potential biases that could arise from personal investments in the outcome of the research. In contrast, individuals with no legal background, those who are research participants, and individuals with experience in human subject research can still contribute to the IRB's function in various ways, as long as their involvement does not create a conflict of interest. For example, having members with broad expertise can enhance the IRB's discussions and deepen its understanding of diverse research contexts and ethical considerations.