Certification for IRB Professionals (CIP) Practice Exam

How often must IRBs conduct continuing review of research studies?

1. Every week

2. At least annually

3. Only at the beginning of the study

4. Every five years

The correct answer is: At least annually

The requirement for Institutional Review Boards (IRBs) to conduct continuing review of research studies is grounded in the ethical oversight of research involving human subjects. The correct answer states that IRBs must perform this review at least annually. This annual review is essential to ensure that the research continues to comply with ethical standards and that the risks to participants remain acceptable in light of any new information that may have emerged. Continuing reviews help to reaffirm that the study still aligns with the initial ethical considerations evaluated during the initial review phase. Moreover, conducting these reviews annually allows IRBs to monitor ongoing research activities and any changes in the research that might impact participant safety or the informed consent process. Regulatory guidelines require that research involving human subjects undergoes periodic review, and specifying a timeline of at least annually ensures oversight remains vigilant. This annual requirement supports the principle of respect for persons, beneficence, and justice as it pertains to the research subjects involved.